Clinical Trials

Overview

Clinical trials are vital in testing the safety and efficacy of new treatments and approaches. Our researchers are national leaders in multiple national cooperative groups, including the NRG and Alliance Groups, and are principal investigators on cutting-edge treatment trials.

Multiple other RMAS faculty oversee Investigator-Initiated Trials (IIT) at the Moores Cancer Center, many of which are not available elsewhere.

Example CPRM Bioinformatics Publications

• Phase I Trial of Intravenous Oncolytic Vaccinia Virus (GL-ONC1) with Cisplatin and Radiotherapy in Patients with Locoregionally Advanced Head and Neck Carcinoma.
• Safety and Efficacy of a Five-Fraction Stereotactic Body Radiotherapy Schedule for Centrally Located Non-Small-Cell Lung Cancer: NRG Oncology/RTOG 0813 Trial.
• Phase III Trial: Adjuvant Pelvic Radiation Therapy Versus Vaginal Brachytherapy Plus Paclitaxel/Carboplatin in High-Intermediate and High-Risk Early Stage Endometrial Cancer.
• Prospective, Randomized Control Trial Investigating the Impact of a Physician-Communicated Radiation Therapy Plan Review on Breast Cancer Patient-Reported Satisfaction.
• Establishing a New Clinical Role for Medical Physicists: A Prospective Phase II Trial