Intensity Modulated Radiation Therapy (IMRT) Treatment
In recent years, however, a sophisticated form of 3DCRT known as intensity modulated radiation therapy (IMRT) has been increasingly used in GI tumor patients. Unlike conventional approaches, IMRT using highly modulated beams designed using sophisticated computerized optimization planning. Such beams conform the radiation dose to the shape of the tumor in 3D, reducing the volume of normal surrounding tissues receiving high doses (and thus the risk of treatment related sequelae).
Multiple investigators have reported promising results using IMRT in GI tumor patients (view paper 1 and paper 2).
IMRT plan in a patient with pancreatic cancer
IMRT is particularly appealing in patients with anal cancer (view paper). In such patients, conventional approaches result in the irradiation of large volumes of normal tissues, exposing patients to a wide range of toxicities. IMRT helps minimize the dose to these structures reducing the risk of treatment toxicities (view paper).
IMRT plan in a patient with anal cancer